Barely Significant
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A nurse-led up-titration clinic improves chronic heart failure optimization of beta-adrenergic receptor blocking therapy--a randomized controlled trial.

BMC Res Notes · 2014 · PMC4182807 · PMID 25248944

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highly significantno p-value reported
However, because of the much greater than expected effect of the intervention, the benefits were highly significant.

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a slight trendno p-value reported
Quality of life scores On the MLWHF, there was no significant difference between the groups at any time point, although there was a slight trend towards the intervention group having slightly less deterioration over the six months in overall quality of life than the UC control group (mean difference +6.7 ± 16.2 vs +9.5 ± 10.8; p = 0.6).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.