Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?

Exp Mol Med · 2014 · PMC4183942 · PMID 25213768

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markedly significantno p-value reported

43 For example, the expression of ICAM-1 in asthma patients was significantly higher than in healthy controls, and more markedly significant differences were observed in severe asthma attacks. 44 Thus, methods to reduce ICAM-1 and VCAM-1 expression would be of interest in the development of novel therapeutic methods for asthma.

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