XG-102 administered to healthy male volunteers as a single intravenous infusion: a randomized, double-blind, placebo-controlled, dose-escalating study.

The geometric mean dose-normalized C max for the 80 μg/kg dose is higher than and outside the 90% CIs for the geometric mean dose-normalized C max for the other doses, suggesting that there may be an increasing trend in C max /dose, which is not conclusively demonstrated due to the small sample size (six subjects per dose).

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