Interestingly, the highly significant association found between P-cadherin and CD147 is in accordance with the above-described reports and also with our previous data, showing that P-cadherin induces an invasive behavior in breast cancer cells through the activation of MMP1 and MMP2 [ 28 ].
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The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype.
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