Low birth weight is a risk factor for severe retinopathy of prematurity depending on gestational age.

For infants born GA ≥26 weeks, all variables reflecting prenatal growth restriction, regardless growth reference or definition, were highly significant as risk factors as follows: BWSDS Sweden for GA 26–27 weeks and for GA 28–29 weeks ( p-values <0.01); SGA Sweden for GA 26–27 weeks ( p <0.001); BWSDS Canada for GA 26–27 weeks and for GA 28–29 weeks ( p-values <0.01); SGA Canada for GA 26–27 weeks and for GA 28–29 weeks ( p-values <0.01); severe growth restriction (Canada) for GA 26–27 weeks and for GA 28–29 weeks ( p <0.001).

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