Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.

Pattern of distribution of mutations across the HBV genome among different stages of liver diseases The prevalence of mutations, which were showing an increasing trend from nLF (no liver fibrosis) to HCC through LF (liver fibrosis) and LC (liver cirrhosis) is summarized in Table 3 .

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