Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.

Alzheimers Res Ther · 2014 · PMC4198935 · PMID 25324900

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hedged sentences

0.0007

closest p · 0.0× alpha

0.0007

boldest claim

The sentences

highly significantp = 7.0E-4actually significant

There was highly significant association of H2-tagging rs8070723-G allele with reduced risk of LOAD in the Mayo Clinic cohort (odds ratio = OR = 0.81, p = 7.0E-4) with remarkably similar OR estimates in the JS and RS series (Additional file 1 : Table S3) and in the independent ADGC cohort (OR = 0.89, p = 1.3E-4) (Table 1 ).

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did not achieve significanceno p-value reported

H1c subhaplotype did not achieve significance in the Mayo Clinic, ADGC or Mayo + ADGC cohorts.

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