The age- and sex-adjusted risk of any ICH was higher in the rt-PA treated group than the rt-PA non-treated group, but this association failed to reach significance after adjustment for multiple confounding factors. rt-PA treatment was not associated with risk of symptomatic ICH and gastrointestinal bleeding.
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Intravenous thrombolysis with recombinant tissue plasminogen activator for ischemic stroke patients over 80 years old: the Fukuoka Stroke Registry.
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