Gene-based rare allele analysis identified a risk gene of Alzheimer's disease.

PLoS One · 2014 · PMC4203677 · PMID 25329708

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highly significantno p-value reported

Furthermore, the associations of APOE and TREM2 with AD were highly significant, even in gene-based rare allele analysis, which implies that further deep sequencing of these genes is required in AD heritability studies. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2014 Apr 7; Accepted 2014 Aug 25; Collection date 2014.

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