Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study.

Highly significant differences (p<0.001) were identified in all patients recruited into ADVANCE and the PARTNER-B MM arm for a number of key cardiovascular endpoints including atrial fibrillation, coronary artery disease, cerebrovascular disease, Logistic EuroSCORE and the proportion of patients with New York Heart Association (NYHA) class III or IV HF.

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