extremely significantp = 1e-7
Nevertheless, the observed degree of overlap was extremely significant (5 sites in both log-phase #1 and #2, p = 1e-7; 9 sites in both log-phase #1 and heat-shock, p = 3e-15; 14 sites in both log-phase #2 and heat-shock, p = 2e-18; all p -values computed by hypergeometric distribution), due to the vast number of possible nucleotides evaluated from throughout the transcriptome ( Figure 3 , Table 1 ).