Importantly, IGFBP-2 concentrations showed a highly significant correlation with those of IGF-I in the serum of rabbits, which was much less pronounced for IGFBP-4 or even absent for IGFBP-3.
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Validation of serum IGF-I as a biomarker to monitor the bioactivity of exogenous growth hormone agonists and antagonists in rabbits.
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