Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoire.

As expected, a highly significant difference (p < 0.0001) was observed between the activity of the unmutated AS and CS minimal promoters in NFS-5 (Figure 2 B) and 18–81 (Figure 2 C) cells, while vector containing only the kappa enhancer exhibited little activity.

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