Genome-wide analyses and functional classification of proline repeat-rich proteins: potential role of eIF5A in eukaryotic evolution.

Although frequencies of tandem repeats of Glu, Pro and Leu showed an increasing trend in more complex organisms, the frequency increases were much smaller (Leu repeat, <2 fold in human over E. coli ) or inconsistent (Glu repeats), compared to those of Pro repeats ( Fig. 5C ).

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