Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians.

In a similar analyses for reclassification based on a mGFR threshold of 45 ml/min/1.73 m 2 the CKD-Epi_cr-cys equation tended to improve classification compared with all other equations; the NRI was statistically significant compared with the BIS_cr (NRI = 15.8, p = 0.04), marginally significant compared with the CKD-EPI_cr (NRI = 20.6, p = 0.08), and not significant versus the CKD-Epi_cys (NRI = 9.7, p = 0.20), and the BIS_cr-cys equation (NRI = 2.9, p = 0.16) (Additional file 2 : Table S2).

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