Nonetheless, wholesale discarding of marginally significant “hits” will discount some true associations within the mix of statistical artifacts.
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GWATCH: a web platform for automated gene association discovery analysis.
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The sentences
The idea is to visualize association results across a gene region (e.g., one that may include a highly significant SNP association) for all the tests performed (on the same or different cohorts) and for all the neighboring, potentially proxy SNPs (i.e., SNPs which track the neighboring causal, disease-affecting SNP due to the linkage disequilibrium [LD]) for the same tests.