Combinatorial modulation of signaling pathways reveals cell-type-specific requirements for highly efficient and synchronous iPSC reprogramming.

Stem Cell Reports · 2014 · PMC4223696 · PMID 25358786

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When culturing reprogrammable MEFs transduced with these vectors in Dox plus 3c, we observed a strong and highly significant increase in the number of Oct4-GFP + cells with KDM2B and a more modest response with SMARCC1 ( Figure 4 C).

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