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Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma.

Elife · 2014 · PMC4227045 · PMID 25329343

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highly significantno p-value reported
Therefore, the study of signaling factors that regulate inner ear synapse density and synaptic regeneration after acoustic injury is highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.