Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition.

Breast Cancer Res · 2014 · PMC4227109 · PMID 24981670

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0550

boldest claim

The sentences

borderline significantP = 0.051so close (0.05 < p ≤ 0.1)

Association of PIK3CA mutation status and gene signatures with Ki67 There was a borderline significant difference ( P = 0.051) in baseline Ki67 between PIK3CA WT and mutation samples, with patients with the mutation having lower levels of proliferation (Table 2 ).

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a trend towards significanceP = 0.051so close (0.05 < p ≤ 0.1)

Mutations were associated with markers of good prognosis such as progesterone receptor positivity (PgR+) ( P = 0.006), low grade ( P = 0.028) and luminal A subtype ( P = 0.039), with a trend towards significance with degree of ER positivity ( P = 0.051) and low levels of Ki67 ( P = 0.051).

also in 2,760 other papers

a slight trendP = 0.055so close (0.05 < p ≤ 0.1)

It did, however, show a slight trend towards correlation with ER protein expression ( r = 0.240, P = 0.055).

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