Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease.

43 , 44 A recent Cochrane meta-analysis including 431 patients across 18 studies also showed a highly significant improvement in dyspnea in nonhypoxemic COPD patients who would not otherwise meet physiological criteria for oxygen therapy. 45 Breathing supplemental oxygen versus compressed air improved dyspnea and endurance during exercise in COPD patients 46 and, in those patients who showed an improvement in

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