Barely Significant
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CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin.

Nucleic Acids Res · 2014 · PMC4231773 · PMID 25294833

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highly significantno p-value reported
Depletion of CTCF showed a highly significant reduction in H3.3 at the sites MFSD5, CORO1C and TMBIM6 as compared to cells treated with unspecific siRNA (Figure 8C ).

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