highly significantP = 0·001
Night-time sleep disturbance There were highly significant reductions in night-time sleep disturbances (Fig. 4a ), with the median baseline VAS of 71 (21·75–78·5) being reduced to 10 (0–25·25) ( P = 0·001) by levocetirizine plus hydroxyzine and 17 (0–24·75) ( P = 0·002) by levocetirizine monotherapy.