Barely Significant
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Safety limitations of MR-HIFU treatment near interfaces: a phantom validation.

J Appl Clin Med Phys · 2012 · PMC4241267 · PMID 22402391

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may be significantno p-value reported
By performing computer simulations, as well as experiments, Nell and Myers (7) determined that even if the focal spot is targeted more than 4 cm from bone, heating at the interface may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.