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Chronic escitalopram treatment attenuated the accelerated rapid eye movement sleep transitions after selective rapid eye movement sleep deprivation: a model-based analysis using Markov chains.

BMC Neurosci · 2014 · PMC4243313 · PMID 25406958

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a decreasing trendno p-value reported
In the onset phase, the frequency of wakeful periods showed a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.