Barely Significant
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Shedding of APP limits its synaptogenic activity and cell adhesion properties.

Front Cell Neurosci · 2014 · PMC4253958 · PMID 25520622

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 0.0001actually significant
Both APP mutations resulted in a highly significant reduction in sAPP total secretion ( p < 0.0001; Figures 2A,B ).

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