In contrast, sera from 2 subjects (NAA16 and AA12), which did not directly increase basophil activation, significantly inhibited allergen-induced activation, while serum from a third subject (NAA2) exhibited an inhibitory effect of borderline significance ( Fig 2 , B , and Fig E4 , B , in this article's Online Repository at www.jacionline.org ).
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"Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation.
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