Total fructose intake and risk of hypertension: a systematic review and meta-analysis of prospective cohorts.

However, separate analyses pooling data at each quantile found a significant protective association of fructose intakes at the third (9.5%E, RR = 0.95, 95% CI, 0.92–0.98, p = 0.0004) and fourth (11.2%E, RR = 0.93, 95% CI, 0.93–0.98, p = 0.001) quantiles, and a borderline significant protective association at intakes equivalent to the second quantile (7.9%E, RR = 0.97, 95% CI, 0.95–1.00, p = 0.05; Fig. 3 ).

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