DNA extraction protocols cause differences in 16S rRNA amplicon sequencing efficiency but not in community profile composition or structure.

Microbiologyopen · 2014 · PMC4263514 · PMID 25257543

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP < 2 × 10 −16actually significant

Results Bacterial quantification The effect of extraction methodology on the concentration of the bacterial 16S rRNA gene was highly significant (Repeated measures ANOVA, F = 61.5, P < 2 × 10 −16 ; Fig. 1 A).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.