Immunology of naturally transmissible tumours.

85 It may be significant that a quarter of DFTD tumours were found to have lymphocytes at the periphery of the tumour mass and our own observations indicate that CD3-positive cells can gather at the edges of tumours without obvious infiltration. 40 , 75 Lack of infiltration may indicate that the microenvironment is promoting tumour growth and immunosuppression (as in ref. 86 ), or these CD3 cells may be tolerogenic (i.e.

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