The superiority of ivabradine (efficacy and safety) was also shown by Kaplan–Meier curves generated for the primary endpoints in both groups (ivabradine as monotherapy and combination therapy ivabradine plus metoprolol), log-rank tests being highly significant between days 4–30 of treatment (Fig. 4 ).
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Ivabradine Versus Beta-Blockers in Patients with Conduction Abnormalities or Left Ventricular Dysfunction Undergoing Cardiac Surgery.
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