The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial.

Although the percentage of responders in the ACT1-treated group (63%) reaching 50% closure just failed to reach significance ( P =0.060) over those receiving SOC-alone (43%), for those participants adherent to protocol without missing data points (PP population) the incidence of ulcers exhibiting 50% closure in ACT1-treated participants significantly exceeded those in SOC-alone (80 vs. 51% P =0.013; Table 2 ).

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