Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes.

Mucosal Immunol · 2015 · PMC4269809 · PMID 25052763

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highly significantno p-value reported

In mice immunized with rAd-SHA2(Opt)FCD40L, highly significant levels of nasal IgA and circulatory IgG1 and IgG2a Abs with titers greater than fourfold compared with rAd-SHA2(wt) were also generated.

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