Use of propranolol blockade to explore the pharmacology of GSK961081, a bi-functional bronchodilator, in healthy volunteers: results from two randomized trials.

Addition of salbutamol 600 μg to ipratropium 40 μg showed a small trend to increased sGaw compared with when salbutamol 600 μg was added to ipratropium 40 μg in the presence of propranolol (Fig. 2 b: 9-h time point), but the comparison showed that salbutamol + ipratropium + propranolol was non-inferior to salbutamol + ipratropium (Table 2 ).

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