Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage.

Analysis of mRNA expression of HO-1, a Hb/heme- and oxidative stress-inducible protein responsible for intracellular heme degradation, revealed a highly significant up-regulation at both 24 and 72 hours following IVH (Figure 2 J).

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