Accurate mitochondrial DNA sequencing using off-target reads provides a single test to identify pathogenic point mutations.

Genet Med · 2014 · PMC4272251 · PMID 24901348

Europe PMC DOI

hedged sentence

0.0243

closest p · 0.5× alpha

0.0243

boldest claim

The sentences

marginally significantP = 0.02431actually significant

This corresponds to an error rate of 24 of 762,174 or 0.0031% for WES, which shows a marginally significant increase as compared to the Sanger rate (Poisson exact ratio test ( P = 0.02431) of rate ratio = 1).

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