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Protective effect of exclusive breastfeeding against hand, foot and mouth disease.

BMC Infect Dis · 2014 · PMC4273484 · PMID 25471294

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an increasing trendno p-value reported
Asia-Pacific countries have experienced an increasing trend of HFMD outbreaks in the past decades, resulting in thousands of deaths among the children [ 7 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.