STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy.

Cancers (Basel) · 2014 · PMC4276953 · PMID 25268165

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highly significantno p-value reported

Subsequently, the authors combined RNAi against STAT3 and ErbB2 with irradiation in an U251 xenograft mouse model, which led to a highly significant inhibition of tumor growth compared to single RNAi treatment without toxic effects in normal astrocytes from the brain of Wistar rats [ 45 ].

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