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Clinical features and outcomes in patients with human immunodeficiency virus-negative, multicentric Castleman's disease: a single medical center experience.

Blood Res · 2014 · PMC4278007 · PMID 25548759

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might be significantno p-value reported
Extravascular fluid accumulation and disseminated disease might be significant prognostic factors for multicentric CD, and their prognostic relevance requires validation in future studies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.