Detained introns are a novel, widespread class of post-transcriptionally spliced introns.

This enrichment is highly significant ( P = 2.2 × 10 −15 ), and when the direction and magnitude of gene expression changes in our CB19 data or the previously published doxorubicin treatment were compared with each other, the correlation was also highly significant ( P = 1.4 × 10 −14 ), indicating that both p53-activated and p53-repressed genes change in similar directions and magnitudes in CB19-treated cells and doxorubicin-treated cells ( Fig. 7A ).

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