A novel mechanism for Prp5 function in prespliceosome formation and proofreading the branch site sequence.

Genes Dev · 2015 · PMC4281567 · PMID 25561497

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may not be significantno p-value reported

Although such a small increase in the affinity of E235A for the spliceosome may not be significant to account for the enhancer phenotype, it contrasted with the suppressor mutants N399D and TAG in its affinity for the spliceosome relative to the wild-type protein.

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