highly significantp = 6.0 × 10 −7
Categorization of subjects based on high systolic blood pressure (≥75th percentile) and low systolic blood pressure (≤25th percentile) generated a highly significant difference in slope of the principal component for CVD risk factors ( p = 6.0 × 10 −7 ), since individuals having high systolic blood pressure tended to have negative slopes (average = −0.37) while the group with low initial blood pressure did not show any change in slope (average = 0.01).