A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS.

Gut · 2015 · PMC4283622 · PMID 24647007

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borderline significantno p-value reported

15–17 For loci at which significant or borderline significant associations between genetic variants and toxicity were detected, we performed fine mapping studies by using the methods above to impute all SNPs in a 1.5 Mb flanking region, in order to refine the association signal.

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