Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG.

Oncoscience · 2014 · PMC4284617 · PMID 25594042

Europe PMC DOI

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highly significantno p-value reported

Our study is highly significant as it demonstrates that two safe therapy modalities, LOFU and low-dose 17AAG, when combined, could result in significant PC cell death and increase the therapeutic ratio for tumor control.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.