Examples of genes with highly significant changes for upregulated stomach markers are Cldn18 , Muc1, Tff2 and Gif , and for downregulated intestinal markers, Olfm4 , Muc2, Cdx1, Cdh17, Tff3 , Muc13 and Reg4 ( Fig. 3c and Supplementary Fig. 6b ).
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Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.
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