The most important point to highlight after conducting this study is that although CHI3L1 gene promoter variants showed highly significant association with YKL-40 levels, only the latter revealed a significant association with multiple atherosclerosis-related traits and the risk of PAD.
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Circulating YKL-40 level, but not CHI3L1 gene variants, is associated with atherosclerosis-related quantitative traits and the risk of peripheral artery disease.
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