Sixty min postinjection the absolute uptake of [ 68 Ga]FSC-(RGD) 3 in the α v β 3 positive M21 tumor was 4.25 ± 0.64% ID/g, but only 1.13 ± 0.38% ID/g in the contralateral negative M21L tumor, being highly significant and confirming the receptor-selective uptake found in vitro .
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[(68)Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold-synthesis and evaluation.
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