Barely Significant
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Microstructured zirconia surfaces modulate osteogenic marker genes in human primary osteoblasts.

J Mater Sci Mater Med · 2015 · PMC4289972 · PMID 25578704

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highly significantno p-value reported
(i) significantly down-regulated ALP mRNA expression on YZ-SE and YZ-SEH after 3 days, (ii) decreased COL mRNA on YZ-SE and YZ-SEH after 3 days, (iii) highly significant enhanced OCN gene expression on YZ-SE and YZ-SEH after 1 and 3 days of culture.

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