marginally significantP = 0.097
As represented by the stratification analysis ( Table 2 ), this effect, although marginally significant in POSH data ( P = 0.097, HR = 0.75, 95% C.I.= 0.53, 1.06), has similar patterns in both data sets ( Figure S1 ) and the significance is largely improved in the pooled analysis ( P = 0.0035, HR = 0.73, 95% C.I. = 0.59, 0.9).