Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

J Immunother Cancer · 2014 · PMC4292414

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may be significantno p-value reported

Together, these data suggest that there may be significant immune heterogeneity between different tumors within a single patient with metastatic melanoma.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.