Bidirectional global spontaneous network activity precedes the canonical unidirectional circuit organization in the developing hippocampus.

J Comp Neurol · 2014 · PMC4293468 · PMID 24357090

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may be significantno p-value reported

The distal CA3 origin of GNA and SPWs may be significant, in that this region is adjacent to CA2 and receives strong input from the supramammillary nucleus that has been implicated in controlling the frequency of the theta rhythm and the spread of epileptic activity in the hippocampus (Chevaleyre and Siegelbaum, 2010 ; Lein et al., 2005 ; Ochiishi et al., 1999 ).

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